| 64 | Alexandra Burnett (WESLEYAN) def. Mia Thomann (WILLIAMS) 7-6 (7-3), 6-2 |
| 64 | Sarah Youngberg (WESLEYAN) def. Lejla Guster (ENDICOTT) 6-3, 6-0 |
| 64 | Deliala Friedman (AMHERST) def. Macie Carlos (WESLEYAN) 6-1, 6-4 |
| 64 | Jackie Soloveychik (WESLEYAN) def. Bhakti Parwani (BRANDEIS) 4-6, 6-4, 10-5 |
| 64 | Leila Epstein (WESLEYAN) def. Charis Vogler (NICHOLS) 6-1, 6-0 |
| 64 | Lane Durkin (WESLEYAN) def. Chahana Budhbhatti (BRANDEIS) 6-1, 6-3 |
| 32 | Olivia Soffer (BABSON) def. Alexandra Burnett (WESLEYAN) 6-1, 6-1 |
| 32 | Sarah Youngberg (WESLEYAN) def. Pan Manataweewat (SPR) 6-0, 6-1 |
| 32 | Matia Cristiani (BABSON) def. Jackie Soloveychik (WESLEYAN) 6-3, 6-3 |
| 32 | Leila Epstein (WESLEYAN) def. Amy Cui (AMHERST) 6-3, 6-3 |
| 32 | Lane Durkin (WESLEYAN) def. Julia Ross (BOWDOIN) 6-3, 6-2 |
| 16 | Sarah Youngberg (WESLEYAN) def. Rebecca Suarez (BRANDEIS) walkover |
| 16 | Leila Epstein (WESLEYAN) def. Rachel Cranley (TUFTS) 7-6 (7-3), 6-0 |
| 16 | Lane Durkin (WESLEYAN) def. Sophie Diop (AMHERST) 4-6, 6-2, 10-5 |
| QF | Sarah Youngberg (WESLEYAN) def. Olivia Soffer (BABSON) 6-7 (1-7), 6-4, 10-5 |
| QF | Matia Cristiani (BABSON) def. Leila Epstein (WESLEYAN) 6-2, 6-1 |
| QF | Sahana Raman (MIDD) def. Lane Durkin (WESLEYAN) 6-3, 6-2 |
| SF | Sarah Youngberg (WESLEYAN) def. K. Shepherd Johnson (MIT) 6-2, 6-3 |
| F | Matia Cristiani (BABSON) def. Sarah Youngberg (WESLEYAN) 6-0, 6-3 |
